Monday, March 30, 2009

Leflunomide



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arthritis is Did you know there are over 100 types of arthritis? The word "arthritis" itself means "inflammation of the joints" and is a blanket term encompassing everything from gout, hepatitis and systemic lupus erythematosus, to osteoporosis, lyme disease and still's disease. Today, arthritis is ... Arava, arava side effects, what is arava, arava overdose, generic arava, arava medicine information and more... Question 113 Typical rheumatoid arthritis is characterized by Symmetric inflammatory polyarthritis Sparing of axial skeleton except cervical spine Sparing of distal interphalangeal joints All of the above-------------- Question 114 Which of these is not a feature of rheumatoid arthritis? Swollen joints Painful joints Morning stiffness Headache--------------- Question 115 The exact etiology of rheumatoid arthritis is not known but all th LEFLUNOMIDE (Arava) Pharmacology. Leflunomide's active metabolite (M1) inhibits dihydro-oratate dehydrogenase, thereby inhibiting pyrimidine biosynthesis. M1 exhibits immunomodulating and anti-inflammatory effects. Administration and Adult Dosage. PO for rheumatoid arthritis 100 mg/day for 3 days, then 20 mg/day. Reduce dose to 10 mg if 20 mg is not tolerated. Pediatric Dosage. Safety and efficacy not established. Geriatric Dosage. Same as adult dosage. Dosage Forms. This is

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